Genetic drivers of congenital cardiac fibrosis - Nature
A groundbreaking study published in "Nature" this week has pinpointed crucial genetic drivers behind congenital cardiac fibrosis, a severe and often life-threatening complication in children with congenital heart disease. Researchers, leveraging advanced single-cell RNA sequencing and gene editing techniques, identified specific mutations that dysregulate extracellular matrix (ECM) remodeling, fundamentally altering how heart tissue responds to stress from birth.















